Hyaluronate ea sodiume fumanoa haholo liphoofolong le bathong physiologically active substance, letlalong la motho, synovial fluid, umbilical cord, aqueous humor, le ophthalmic vitreous body li ajoa. Boima ba eona ba molek'hule ke 500 000-730 000 Dalton. Tharollo ea eona e na le viscoelasticity e phahameng le profiling. Ke mothusi bakeng sa ophthalmic ophthalmic. E boloka botebo bo itseng ba kamore e ka pele ka mor'a ente ka kamoreng e ka pele. E loketse ho sebetsa. E boetse e sireletsa lisele tsa corneal endothelial le lisele tsa intraocular, e fokotsa mathata a ts'ebetso, 'me e khothalletsa pholiso ea maqeba.
Mohloli oa sodium hyaluronate
Hyaluronate ea sodiumke macromolecule polysaccharide e ntšitsoeng 'meleng oa bovine vitreous. E na le litšobotsi tse tharo: liphutheloana tse thibelang botsofali le ho boloka bocha le ho amohela theknoloji ea baeloji.
Sodium hyaluronate ke e 'ngoe ea likarolo tsa letlalo la motho, ke mucosa ea acid e ajoang ka ho fetesisa' meleng, e teng ka har'a matrix a lithane tse hokahaneng, 'me e na le phello e ntle ea mongobo.
Litšobotsi tsa Sodium hyaluronate
Hyaluronate ea sodium e na le litšoaneleho tse tharo: liphutheloana tse thibelang botsofali le ho boloka bocha le biotechnology. Sodium hyaluronate ke e 'ngoe ea likarolo tsa letlalo la motho le mucose e nang le asiti e ajoang haholo' meleng oa motho. E teng ka har'a matrix a lithane tse hokahaneng 'me e na le phello e ntle ea mongobo.
Melemo ea Sodium Hyaluronate
1. Ho ntlafatsa Pharmacodynamics
Asiti ea Hyaluronicke karolo ea mantlha ea lisele tse hokahaneng joalo ka interstitium ea motho, 'mele oa vitreous le synovial fluid. E na le litšobotsi tsa ho boloka metsi, ho boloka sebaka se kantle ho sele, ho laola khatello ea osmotic, ho tlotsa le ho khothaletsa tokiso ea lisele ka har'a vivo. Joalo ka sejari sa meriana ea mahlo, e ka lelefatsa nako ea ho bolokoa ha lithethefatsi ka holim'a leihlo ka ho eketsa ponahalo ea marotholi a mahlo, ho ntlafatsa bioavailability ea lithethefatsi, le ho fokotsa ho teneha ha lithethefatsi mahlong.
The adjuvant therapy e ka kenngoa ka ho toba ka har'a articular cavity e le lubricant bakeng sa phekolo ea ramatiki, joalo ka ente ea SPIT.
2. Crease Resistance
Boemo ba mongobo ba letlalo bo amana haufi-ufi le litaba tsa hyaluronic acid. Ka ho eketseha ha lilemo, litaba tsa hyaluronic acid letlalong lia fokotseha, tse fokolisang ts'ebetso ea ho boloka metsi ea letlalo le ho hlahisa masoba. Sodium hyaluronate aqueous solution e na le viscoelasticity e matla le lubricity. Ha e sebelisoa holim'a letlalo, e ka etsa filimi e kenang mongobo ho boloka letlalo le le mongobo 'me le benya. Molek'hule e nyane ea hyaluronic acid e ka kenella ka har'a dermis, ea khothaletsa microcirculation ea mali, ea thusa letlalo ho monya limatlafatsi, 'me ea bapala karolo ea bophelo bo botle le e khahlanong le wrinkles.
3. Phello ea Moisturizing
Phello ea mongobo ke karolo ea bohlokoa ka ho fetisisa easodium hyaluronate ka litlolo. Ha ho bapisoa le li-moisturizers tse ling, mongobo o lekanyelitsoeng oa tikoloho e potolohileng ha o na tšusumetso e fokolang holim'a phello ea oona ea mongobo. Sebopeho sena se ikhethang se ikamahanya le letlalo ka linako tse fapaneng tsa selemo, mongobo o fapaneng oa tikoloho, joalo ka mariha a omileng le lehlabula le nang le metsi, le litlhoko tsa phello ea litlolo tse nang le moisturizing. Ho boloka mongobo oa sodium hyaluronate ho amana le boima ba eona le boima ba limolek'hule.
4. Liphello Tsa Phepo
Sodium hyaluronate ke ntho ea tlhaho ea tlhaho letlalong, 'me exogenous sodium hyaluronate ke tlatsetso ho endogenous sodium hyaluronate letlalong. Sodium hyaluronate e nang le boleng bo tlaase e ka kenella ka har'a letlalo la letlalo, e khothalletsa phepelo ea phepo ea letlalo le ho ntša litšila, kahoo e thibela ho tsofala ha letlalo, 'me e na le karolo ea cosmetology le botle. Tlhokomelo ea letlalo ke ea bohlokoa ho feta litlolo tse ling 'me e fetohile takatso ea batho ba kajeno ea ho boloka sefahleho sa sefahleho.
5. Tokiso le Thibelo ea Tšenyo ea Letlalo
Letlalo le chesoa kapa le chesoa ke khanya ea letsatsi, joalo ka ho ba bofubelu, ho ntšofala, ho ebola, joalo-joalo, haholo-holo ke mahlaseli a ultraviolet mahlaseli a letsatsi. Sodium hyaluronate e ka khothalletsa ho tsosolosoa ha letlalo le lemetseng ka ho khothalletsa ho ata le ho arohana ha lisele tsa epidermal le ho senya li-radicals tse se nang oksijene. Tšebeliso ea pele e boetse e na le phello ea thibelo. Mokhoa oa eona oa ts'ebetso o fapane le monyo oa ultraviolet o sebelisoang hangata ho sireletsa letsatsi. Ka hona, acid ea hyaluronic le ultraviolet e monyang lihlahisoa tsa letlalo tsa letlalo tsa letsatsi li na le phello ea synergistic, e ka fokotsang phetiso ea mahlaseli a ultraviolet le ho lokisa tšenyo ea letlalo e bakoang ke palo e nyenyane ea mahlaseli a ultraviolet, kahoo e bapala karolo e 'meli ea tšireletso.
Motsoako oa sodium hyaluronate le EGF (epidermal growth factor) e ka potlakisa ho tsosolosoa ha lisele tsa epidermal le ho etsa hore letlalo le be bonolo, le boreleli le ho phutholoha. Ha letlalo le e-na le ho chesa hanyenyane le maqeba, ho sebelisoa ha litlolo tsa metsi tse nang le sodium hyaluronate holim'a metsi ho ka kokobetsa bohloko le ho potlakisa ho fola ha letlalo le lemetseng.
6. Lubrication le Film Formation
Sodium hyaluronate ke mofuta oa polymer e nang le lubrication e matla le thepa ea ho etsa lifilimi. Lihlahisoa tsa Skincare tse nang le sodium hyaluronate li na le lubrication e hlakileng le maikutlo a matle a letsoho ha li sebelisoa. Ha e sebelisoa letlalong, filimi e ka thehoa holim'a letlalo, e leng se etsang hore letlalo le ikutloe le le bonolo ebile le le mongobo, 'me le sireletsa letlalo. Lihlahisoa tsa moriri tse nang le sodium hyaluronate li ka etsa lera la filimi holim'a moriri, e ka khonang ho kolobisa, ho tlotsa, ho sireletsa moriri, ho felisa motlakase o tsitsitseng, le ho etsa hore moriri o be bonolo ho o kopanya, o motle le oa tlhaho.
7. Ho teteana
Hyaluronate ea sodium e na le viscosity e phahameng ka tharollo e nang le metsi. E ka phetha karolo ea ho tiisa le ho tsitsisa litlolo.
8. Liphello tsa Pharmacological tsa Sodium Hyaluronate
Lintho tse sebetsang tsa fisioloji li fumaneha ka bongata liphoofolong le bathong 'me li ajoa letlalong la motho, mokelikeli oa synovial oa manonyeletso, mokhubu, metlae ea metsi, le 'mele oa mahlo oa vitreous. Boima ba molek'hule ke 500000-730000 Dalton. Tharollo ea eona e na le viscoelasticity e phahameng le ho etsisa. Ke mothusi bakeng sa ophthalmic ophthalmic. E boloka botebo bo itseng ba kamore e ka pele ka mor'a ente ka kamoreng e ka pele, e loketseng ho sebetsa. E boetse e sireletsa lisele tsa corneal endothelial le lisele tsa intraocular, e fokotsa mathata, 'me e khothalletsa pholiso ea maqeba.
Nako ea poso: Aug-23-2023
